toxreviewТоксикологический вестникToxicological Review0869-79223034-4611Federal Scientific Center of Hygiene named after F.F. Erisman10.36946/0869-7922-2020-1-54-60toxreview-261Research ArticleЭКОЛОГИЧЕСКАЯ ТОКСИКОЛОГИЯECOLOGICAL TOXICOLOGYВЛИЯНИЕ ГУМИНОВЫХ КИСЛОТ НА МОДИФИКАЦИЮ БИОАКТИВНОСТИ МАГНИТНЫХ НАНОЧАСТИЦINFLUENCE OF HUMIC ACIDS ON THE MODIFICATION OF THE BIOACTIVITY OF MAGNETIC NANOPARTICLESБондаренкоЛ. С.BondarenkoL. S.

Бондаренко Любовь Сергеевна, аспирант, инженер

125993, г. Москва

125993, Moscow

l.s.bondarenko92@gmail.comУчановП. В.UchanovP. V.

Учанов Павел Владимирович, младший научный сотрудник

119071, г. Москва

119071, Moscow

p.uchanov@gmail.comЧистяковаН. Г.ChistyakovaN. G.

Чистякова Наталья Георгиевна, доцент

119992, г. Москва

119992, Moscow

nchistyakova@yandex.ruТереховаВ. А.TerekhovaV. A.

Терехова Вера Александровна, доктор биологических наук, профессор, заведующая лабораторией экотоксикологического анализа почв, МГУ им. М.В.Ломоносова

119992, г. Москва; 117997, Москва

119992, Moscow; 117997, Moscow

vterekhova@gmail.comКыдралиеваК. А.KydralievaK. A.

Кыдралиева Камиля Асылбековна, доктор химических наук, профессор

125993, г. Москва; 119992, г. Москва

125993, Moscow; 119992, Moscow

kamila.kydralieva@gmail.comФГБОУ ВО Московский авиационный институт (Национальный исследовательский университет)РоссияMoscow Aviation Institute, National Research University, Ministry of Science and Higher EducationRussian FederationФГБУН Институт проблем экологии и эволюции им. А.Н. Северцова Российской академии наукРоссияA.N. Severtsov Institute of Ecology and Evolution, Russian Academy of SciencesRussian FederationФГБОУ ВО Московский государственный университет имени М.В.ЛомоносоваРоссияLomonosov Moscow State University, Ministry of Science and Higher EducationRussian FederationФГБОУ ВО Московский государственный университет имени М.В.Ломоносова; ФГБОУ ВО Российский экономический университет им. Г.В. ПлехановаРоссияLomonosov Moscow State University, Ministry of Science and Higher Education; Plekhanov Russian University of Economics, Ministry of Science and Higher EducationRussian FederationФГБОУ ВО Московский авиационный институт (Национальный исследовательский университет); ФГБОУ ВО Московский государственный университет имени М.В.ЛомоносоваРоссияMoscow Aviation Institute, National Research University, Ministry of Science and Higher Education; Lomonosov Moscow State University, Ministry of Science and Higher EducationRussian Federation202024022020015460Copyright © Бондаренко Л.С., Учанов П.В., Чистякова Н.Г., Терехова В.А., Кыдралиева К.А., 20202020Бондаренко Л.С., Учанов П.В., Чистякова Н.Г., Терехова В.А., Кыдралиева К.А.Bondarenko L.S., Uchanov P.V., Chistyakova N.G., Terekhova V.A., Kydralieva K.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.toxreview.ru/jour/article/view/261

В стандартизованных тест-системах проведены исследования воздействия магнитных наноматериалов на основе железа на живые системы – фотосинтезирующие растения. Проведено сравнение действия наночастиц магнетита и маггемита после стабилизации их поверхности гуминовыми кислотами по реакциям микроводорослей Scenedesmus quadricauda (Turp.) Breb. и проростков семян высших растений – горчицы белой Sinapis alba L. Оценивали динамику ростовых тест-функций по изменению флуоресценции хлорофилла в суспензии микроводорослей и по изменению длины корней проростков семян при инкубации с исследуемыми препаратами относительно контрольных вариантов (без препаратов). Установлено, что обработка гуминовыми кислотами, достаточная для стабильности наночастиц железа по показателям фазового состояния, не обеспечивает снижение токсичности маггемита в обеих тест-системах. Обсуждаются возможные механизмы изменения экотоксичности синтезированных магнитных нанопрепаратов железа при взаимодействии с живыми системами в среде их роста.

The influence of iron-based magnetic nanomaterials on living systems — photosynthetic plants – have been studied in standardized test systems. The effects of magnetite and maghemite nanoparticles after stabilization of their surface with humic acids by the reactions of microalgae Scenedesmus quadricauda (Turp.) Breb. and sprouts of seeds of higher plants - white mustard Sinapis alba L. – have been compared. The dynamics of growth test functions have been evaluated by changing the fluorescence of chlorophyll in a suspension of microalgae and by changing the length of the roots of seed seedlings during incubation with the studied drugs relative to the control variants (without drugs). It has been found that the treatment with humic acids sufficient for the stability of iron nanoparticles in terms of the phase state does not reduce the toxicity of maghemite in both test systems. Possible mechanisms for changing the ecotoxicity of synthesized magnetic iron nanopreparations in interaction with living systems in their growth environment are discussed.

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The authors declare that there are no conflicts of interest present.