<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">toxreview</journal-id><journal-title-group><journal-title xml:lang="ru">Токсикологический вестник</journal-title><trans-title-group xml:lang="en"><trans-title>Toxicological Review</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-7922</issn><issn pub-type="epub">3034-4611</issn><publisher><publisher-name>Federal Scientific Center of Hygiene named after F.F. Erisman</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47470/0869-7922-2022-30-2-79-84</article-id><article-id custom-type="elpub" pub-id-type="custom">toxreview-594</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDY</subject></subj-group></article-categories><title-group><article-title>Влияние пандемии нового коронавируса SARS-CoV-2 и ответных карантинных мер на токсико-эпидемиологическую ситуацию в Азербайджане</article-title><trans-title-group xml:lang="en"><trans-title>The impact of the novel coronavirus SARS-CoV-2 pandemic and quarantine responses on the toxic-epidemiological situation in Azerbaijan</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9321-1899</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Эфендиев</surname><given-names>Исмаил Намик олгы</given-names></name><name name-style="western" xml:lang="en"><surname>Afandiyev</surname><given-names>Ismail Namik</given-names></name></name-alternatives><bio xml:lang="ru"><p>Канд. мед. наук, доцент, главный токсиколог, Клинический Медицинский Центр, ул. Ак. Миркасимова 1, AZ1022, Баку, Азербайджанская Республика.</p><p>e-mail: efendiyevi@gmail.com</p></bio><bio xml:lang="en"><p>Assoc. prof., PhD, chief toxicologist, «Clinical Medicine Center» Public Legal Entity, AZ1022, Baku, Republic of Azerbaijan.</p><p>e-mail: efendiyevi@gmail.com</p></bio><email xlink:type="simple">efendiyevi@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Юридическое лицо публичного права «Клинический Медицинский Центр»</institution><country>Азербайджан</country></aff><aff xml:lang="en"><institution>«Clinical Medicine Center» Public Legal Entity</institution><country>Azerbaijan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>21</day><month>04</month><year>2022</year></pub-date><volume>30</volume><issue>2</issue><fpage>79</fpage><lpage>84</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Эфендиев И.Н., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Эфендиев И.Н.</copyright-holder><copyright-holder xml:lang="en">Afandiyev I.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.toxreview.ru/jour/article/view/594">https://www.toxreview.ru/jour/article/view/594</self-uri><abstract><sec><title>Введение</title><p>Введение. Глобальная пандемия нового коронавируса SARS-CoV-2 явилась не только стрессом и серьёзным испытанием для систем здравоохранения многих стран мира, но и оказала существенное влияние на структуру и число острых отравлений различными химическими веществами и лекарственными средствами.</p><p>Цель исследования — изучение влияния пандемии COVID-19 и введённых в связи с этим карантинных мер на токсико-эпидемиологическую ситуацию в Азербайджане.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Проведён сравнительный анализ базы данных Клинического Медицинского Центра в г. Баку за девять месяцев пандемического периода (20 марта — 21 декабря 2020 г.) с аналогичным периодом 2019 г., а также данными за предыдущее десятилетие (2009–2018 гг).</p></sec><sec><title>Результаты</title><p>Результаты. Была выявлена тревожная динамика резкого роста числа отравлений суррогатами алкоголя и, в первую очередь, метиловым спиртом. Если за 10-летний период 2009–2018 гг. доля больных с отравлениями суррогатами алкоголя составляла всего 0,09% в общей структуре отравлений, то за исследуемый период 2020 г. доля таких интоксикаций возросла до 3,4%. Летальность в группе за аналогичный период 2019 г. составила 5,6% против 50,0% за март–декабрь 2020 г. При этом все фатальные случаи в когорте отравлений суррогатами алкоголя относились к отравлениям метиловым спиртом, таким образом, летальность данной патологии составила 61,5%.</p></sec><sec><title>Выводы</title><p>Выводы. Пандемия COVID-19 и принятые в связи с этим карантинные меры имели существенное влияние на токсико-эпидемиологическую ситуацию в Азербайджане и привели к резкому росту случаев интоксикаций и смертности от отравлений спиртами, и в первую очередь — метанолом.</p></sec><sec><title>Ограничения исследования</title><p>Ограничения исследования. Исследование проводилось на базе единственного в Азербайджане специализированного медицинского учреждения по лечению химических отравлений, поэтому собранная база данных может считаться репрезентационной и релевантной общей токсико-эпидемиологической картине в стране.</p><p>Данное исследование не требует представления заключения комитета по биомедицинской этике.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. The global pandemic of the new coronavirus SARS-CoV-2 has not only been a serious stress test for healthcare systems in many countries around the world, but has also had a significant impact on the structure and number of acute chemical poisoning. The aim of this study was to study the impact of the COVID-19 pandemic and related quarantine measures on the toxic-epidemiological situation in Azerbaijan.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. We conducted a comparative analysis of the database of the Clinical Medicine Center in Baku during the nine months of the pandemic period (March 20 — December 21, 2020) with the data of the same period in 2019 and the previous decade (2009–2018).</p></sec><sec><title>Results</title><p>Results. The alarming dynamics of a significant increase in the number of alcohol surrogates and primarily methyl alcohol poisoning, was revealed. If in the 10-year period of 2009–2018, the intoxication of alcohol surrogates was only 0.09% of the total poisoning cases, then during the study period of 2020 the share of such intoxications increased to 3.4%. The mortality rate in alcohol surrogate intoxication group in 2019 was 5.6% versus 50.0% in March-December 2020. All fatal cases in alcohol surrogate intoxication cohort were related to methyl alcohol poisoning, thus, the mortality rate of this pathology was 61.5%.</p></sec><sec><title>Conclusion</title><p>Conclusion. The COVID-19 pandemic and related quarantine measures had a notable impact on the toxic-epidemiological situation in Azerbaijan and led to a significant increase in alcohol and methanol poisoning and fatality.</p></sec><sec><title>Limitations</title><p>Limitations. The study was conducted on the basis of the only specialized medical institution in Azerbaijan engaged for the treatment of chemical poisoning, therefore the collected database can be considered representative and relevant to the country’s overall toxic-epidemiological situation.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>отравления</kwd><kwd>Азербайджан</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>poisoning</kwd><kwd>Azerbaijan</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hassanian-Moghaddam H., Zamani N., Kolahi A.A., McDonald R., Hovda K.E. Double trouble: methanol outbreak in the wake of the COVID-19 pandemic in Iran - a cross-sectional assessment. Critical Care. 2020; 9; 24(1): 402. https://doi.org/10.1186/s13054-020-03140-w</mixed-citation><mixed-citation xml:lang="en">Hassanian-Moghaddam H., Zamani N., Kolahi A.A., McDonald R., Hovda K.E. Double trouble: methanol outbreak in the wake of the COVID-19 pandemic in Iran - a cross-sectional assessment. Critical Care. 2020; 9; 24(1): 402. https://doi.org/10.1186/s13054-020-03140-w</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Le Roux G., Sinno-Tellier S., Descatha A. COVID-19: home poisoning throughout the containment period. Lancet Public Health. 2020 Jun; 5(6): e315. https://doi.org/10.1016/S2468-2667(20)30111-0</mixed-citation><mixed-citation xml:lang="en">Le Roux G., Sinno-Tellier S., Descatha A. COVID-19: home poisoning throughout the containment period. Lancet Public Health. 2020 Jun; 5(6): e315. https://doi.org/10.1016/S2468-2667(20)30111-0</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Chang A., Schnall A.H., Law R., et al. Cleaning and disinfectant chemical expo- sures and temporal associations with COVID-19 - National Poison Data System, United States, January 1, 2020-March 31, 2020. The Morbidity and Mortality Weekly Report. 2020; 69(16): 496-8. https://doi.org/10.15585/mmwr.mm6916e1</mixed-citation><mixed-citation xml:lang="en">Chang A., Schnall A.H., Law R., et al. Cleaning and disinfectant chemical expo- sures and temporal associations with COVID-19 - National Poison Data System, United States, January 1, 2020-March 31, 2020. The Morbidity and Mortality Weekly Report. 2020; 69(16): 496-8. https://doi.org/10.15585/mmwr.mm6916e1</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Puiguriguer-Ferrando J., Salgado-García E., Nogué-Xarau S.Intoxicaciones atendidas en urgencias durante el confinamiento por la pandemia del COVID-19 [Emergency-department-treated poisonings during home confinement for the COVID-19 pandemic]. (In Spanish). Emergencias. 2020; 32(4): 300-1.</mixed-citation><mixed-citation xml:lang="en">Puiguriguer-Ferrando J., Salgado-García E., Nogué-Xarau S.Intoxicaciones atendidas en urgencias durante el confinamiento por la pandemia del COVID-19 [Emergency-department-treated poisonings during home confinement for the COVID-19 pandemic]. (In Spanish). Emergencias. 2020; 32(4): 300-1.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Grasso A., Resnati C., Lanza A., Berrino L., Villani R. Toxicovigilance during the COVID-19: attention to poisoning related to disinfection. Minerva Anesthesiology. 2020 Dec 15. https://doi.org/10.23736/S0375-9393.20.15010-7</mixed-citation><mixed-citation xml:lang="en">Grasso A., Resnati C., Lanza A., Berrino L., Villani R. Toxicovigilance during the COVID-19: attention to poisoning related to disinfection. Minerva Anesthesiology. 2020 Dec 15. https://doi.org/10.23736/S0375-9393.20.15010-7</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Delirrad M., Mohammadi A.B. New Methanol Poisoning Outbreaks in Iran Following COVID-19 Pandemic. Alcohol and Alcoholism. 2020; 55(4): 347-8. https://doi.org10.1093/alcalc/agaa036</mixed-citation><mixed-citation xml:lang="en">Delirrad M., Mohammadi A.B. New Methanol Poisoning Outbreaks in Iran Following COVID-19 Pandemic. Alcohol and Alcoholism. 2020; 55(4): 347-8. https://doi.org10.1093/alcalc/agaa036</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Soltaninejad K. Methanol Mass Poisoning Outbreak: A Consequence of COVID-19 Pandemic and Misleading Messages on Social Media. International Journal of Occupational and Environmental Medicine. 2020; 11(3): 148-50.</mixed-citation><mixed-citation xml:lang="en">Soltaninejad K. Methanol Mass Poisoning Outbreak: A Consequence of COVID-19 Pandemic and Misleading Messages on Social Media. International Journal of Occupational and Environmental Medicine. 2020; 11(3): 148-50.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Mehrpour O., Sadeghi M. Toll of acute methanol poisoning for preventing COVID-19. Archives of Toxicology. 2020; 94(6): 2259-60. https://dopi.org/10.1007/s00204-020-02795-2</mixed-citation><mixed-citation xml:lang="en">Mehrpour O., Sadeghi M. Toll of acute methanol poisoning for preventing COVID-19. Archives of Toxicology. 2020; 94(6): 2259-60. https://dopi.org/10.1007/s00204-020-02795-2</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">SOCAR Methanol Plant. Available at: https://www.socar.az/socar/en/company/organization/socar-methanol-plant (accessed: July 31, 2021)</mixed-citation><mixed-citation xml:lang="en">SOCAR Methanol Plant. Available at: https://www.socar.az/socar/en/company/organization/socar-methanol-plant (accessed: July 31, 2021)</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
