TOXICOLOGICAL HAZARD ASSESSMENT OF A NEW COMPLEX ORGANOMINERAL MICROFERTILIZER
https://doi.org/10.36946/0869-7922-2020-3-57-61
Abstract
The article is devoted to the study of the nature of the toxic effects of a new complex organic mineral fertilizer on the organism of laboratory animals. The assessment of its toxicity and hazard has been performed with the definition of acute and subacute toxicity parameters, as well as irritant effect on skin and mucous membranes, sensitizing and cumulative effects.
About the Authors
A. V. Istomin
F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor
Russian Federation
Russian Federation
Istomin Aleksandr Viktorovich
141014, Mytishchi, Moscow Region
L. A. Rumyantseva
F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor
Russian Federation
Russian Federation
Rumyantseva Larisa Aleksandrovna
141014, Mytishchi, Moscow Region
O. V. Vetrova
F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor
Russian Federation
Russian Federation
Vetrova Olga Viktorovna
141014, Mytishchi, Moscow Region
I. G. Mikhailov
F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor
Russian Federation
Russian Federation
Mikhailov Ivan Georgievich
141014, Mytishchi, Moscow Region
References
1. Harmful substances in industry: Organic substances: New data from 1974 to 1984: Handbook / ed. by E.N. Levina, I.D. Gadaskina. – L.: Chemistry, 1985 (in Russian).
2. Vetrova O.V., Istomin A.V. Relevance of issues of hygienic safety in the production of mineral fertilizers at the regional level / Materials of the international Congress “Nutrition and health”. – Moscow. – 2013. – P. 20 (in Russian).
3. Harmful substances in the environment. Elements of groups 1-IV of the periodic table and their inorganic compounds. Ref.- Enc. ed. /ed. V.A. Filov et.al. – SPb.: NPO “Professional”, 2012. -464 p (in Russian).
4. SanPiN 1.2.2584-10 “Hygienic requirements for the safety of testing, storage, transportation, sale, use, neutralization and disposal of pesticides and agrochemicals” (Annex 1) (in Russian).
5. Loyt A.O. Preventive toxicology. Primary toxicological assessment of chemical substances. – St. Petersburg: Teza, 1996. – 36 p. (in Russian).
6. Novikov S.M., Fursova T.N. Method of quantitative assessment of cumulative properties of harmful substances / Hygiene and sanitation. – 1987. – No. 10. – Pp. 52-55 (in Russian).
7. MU 1.2.1105-02 “Assessment of the toxicity and hazard of disinfectants”. – M. 2002 (in Russian).
8. Assessment of the toxicity and hazard of chemicals and their mixtures for human health: Guidance. – Moscow: Federal Center for Hygiene and Epidemiology of Rospotrebnadzor, 2014. – 639 p. (in Russian).
9. Potapov A.I., Rakitskiy V.N., Bereznyak I.V. Complex impact of chemical substances in the conditions of industrial and agricultural production /ed. by A.I. Potapov et al. – Moscow: Shiko, 2012. – 176 p. (in Russian).
10. Tulakin A.V., Mekhant’eva L.E. Hygiene of the environment and production environment of mineral fertilizers enterprises / ed. by A. I. Potapov. – M, 2007. – 220 p. (in Russian).
Review
For citations:
Istomin A.V., Rumyantseva L.A., Vetrova O.V., Mikhailov I.G. TOXICOLOGICAL HAZARD ASSESSMENT OF A NEW COMPLEX ORGANOMINERAL MICROFERTILIZER. Toxicological Review. 2020;(3):57-61. (In Russ.) https://doi.org/10.36946/0869-7922-2020-3-57-61
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