Acute toxicity of nanoscale form of 20-hydroxyecdysone in intragastric administration
https://doi.org/10.36946/0869-7922-2021-2-59-63
Abstract
The nanoscale 20-hydroxyecdysone was first proposed and obtained in the form of a clathrate complex with arabinogalactan with an average particle size of 35,3 nm. The study of its acute toxicity has revealed that the product belongs to class VI of relatively harmless drugs according to Hodge and to class 5th in accordance with GOST 32644-2014.
About the Authors
K. T. Erimbetov
All-Russian Research Institute of Physiology, Biochemistry and Animal Nutrition - a branch of the Federal Science Center of Animal Husbandry named after Academy Member L.K. Ernst; Research Center “Park of Active Molecules”
Russian Federation
Russian Federation
Erimbetov Kenes Tagaevich
249013, Kaluga Region
249030, Obninsk, Kaluga Region
A. V. Fedorova
All-Russian Research Institute of Physiology, Biochemistry and Animal Nutrition - a branch of the Federal Science Center of Animal Husbandry named after Academy Member L.K. Ernst
Russian Federation
Russian Federation
Fedorova Alena Vladimirovna
249013, Kaluga Region
A. Ya. Goncharova
Research Center “Park of Active Molecules”
Russian Federation
Russian Federation
Goncharova Anna Yakovlevna
249030, Obninsk, Kaluga Region
O. V. Obvintseva
All-Russian Research Institute of Physiology, Biochemistry and Animal Nutrition - a branch of the Federal Science Center of Animal Husbandry named after Academy Member L.K. Ernst
Russian Federation
Russian Federation
Obvintseva Olga Vital′evna
249013, Kaluga Region
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Review
For citations:
Erimbetov K.T., Fedorova A.V., Goncharova A.Ya., Obvintseva O.V. Acute toxicity of nanoscale form of 20-hydroxyecdysone in intragastric administration. Toxicological Review. 2021;(2):59-63. (In Russ.) https://doi.org/10.36946/0869-7922-2021-2-59-63
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