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ЭПИГЕНЕТИЧЕСКАЯ ТОКСИКОЛОГИЯ: ПЕРСПЕКТИВЫ РАЗВИТИЯ

https://doi.org/10.36946/0869-7922-2018-1-2-7

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Аннотация

Одной из сложных проблем современной экспериментальной токсикологии остаются молекулярные механизмы формирования нарушений здоровья людей в отдаленные сроки после острого либо хронического воздействия токсичных химических загрязнителей окружающей среды (экотоксикантов). Выявление и понимание того, какие эпигенетические изменения индуцируются окружающей средой, и как они могут приводить к неблагоприятным результатам, имеет жизненно важное значение для охраны здоровья населения. Поэтому мы рассматриваем современное понимание эпигенетических механизмов, участвующих в жизненном цикле млекопитающих, и оцениваем имеющиеся данные относительно экологически обусловленной эпигенетической токсичности, а соответственно, формирующейся эпигенетической (эпигеномной) регуляторной токсикологии.

Об авторах

Г. А. Софронов
ФГБНУ Институт экспериментальной медицины
Россия


Е. Л. Паткин
ФГБНУ Институт экспериментальной медицины
Россия


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Для цитирования:


Софронов Г.А., Паткин Е.Л. ЭПИГЕНЕТИЧЕСКАЯ ТОКСИКОЛОГИЯ: ПЕРСПЕКТИВЫ РАЗВИТИЯ. Токсикологический вестник. 2018;(1):2-7. https://doi.org/10.36946/0869-7922-2018-1-2-7

For citation:


Sofronov G.A., Patkin E.L. EPEGENTIC TOXICOLOGY: PERSPECTIVES OF THE DEVELOPMENT. Toxicological Review. 2018;(1):2-7. (In Russ.) https://doi.org/10.36946/0869-7922-2018-1-2-7

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