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МETHOD OF NON-INVASIVE DIAGNOSTICS OF POISONING BY SUBSTANCES OF NEUROPARALYTIC ACTION WITH THE USE OF A BIOSENSOR IN CLINICAL AND FIELD CONDITION

https://doi.org/10.36946/0869-7922-2021-1-38-42

Abstract

The questions of substantiation of the need to create and the prospects of developing a method for non-invasive diagnosis of lesions by compounds of neuroparalytic action in the field that meet modern requirements for sensitivity, specificity and speed are considered. As a result of the research, a method for early and reliable noninvasive diagnosis of lesions by neuroparalytic compounds in the field using an optical biosensor of irreversible cholinesterase inhibitors was proposed.

About the Authors

Е. Т. Gainullina
27th Scientific Center of the Ministry of Defence of the Russian Federation
Russian Federation

Gainullina Era Tazetdinovna

105005, Moscow



S. В. Ryzhikov
Lomonocov Moscow State University, Faculty of Physics
Russian Federation

Ryzhikov Sergey Borisovich

 119991, Moscow

 



V. N. Fateenkov
27th Scientific Center of the Ministry of Defence of the Russian Federation
Russian Federation

Fateenkov Vladimir Nikolaevich

105005, Moscow



М. A. Ponsov
27th Scientific Center of the Ministry of Defence of the Russian Federation
Russian Federation

Ponsov Mikhail Aleksandrovich

105005, Moscow



L. V. Petrakova
27th Scientific Center of the Ministry of Defence of the Russian Federation
Russian Federation

Petrakova Lidiya Vasilievna

105005, Moscow



References

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5. Gainullina E.T., Gulikova D.K., Korneev D.O., Oreshkin D.V., Ryzhikov S.B., Fateenkov V.N. Biosensors as tools of environmental monitoring for organophosphorus nerve agents. Journal of Analytical Chemistry. 2015; V. 70 (7): 771-780.

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7. Gainullina E.T., Korneev D.O., Fateenkov V.N. Optical biosensor of irreversible cholinesterase inhibitors in the air. Patent RF, N 2654294; 2018 (in Russian).


Review

For citations:


Gainullina Е.Т., Ryzhikov S.В., Fateenkov V.N., Ponsov М.A., Petrakova L.V. МETHOD OF NON-INVASIVE DIAGNOSTICS OF POISONING BY SUBSTANCES OF NEUROPARALYTIC ACTION WITH THE USE OF A BIOSENSOR IN CLINICAL AND FIELD CONDITION. Toxicological Review. 2021;1(1):38-42. (In Russ.) https://doi.org/10.36946/0869-7922-2021-1-38-42

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ISSN 0869-7922 (Print)