MORPHOLOGIC SPECIFICITIES OF HEPATOPROTECTIVE EFFECTS OF ANTIHYPOXANTS IN EXPERIMENTAL ACUTE LIVER DAMAGE WITH CARBON TETRACHLORIDE
https://doi.org/10.36946/0869-7922-2019-1-43-48
Abstract
The article presents the results on liver morphologic changes in acute carbon tetrachloride damage and its preventive correction by antihypoxants: complex oxymethyluracil agents (with sodium succinate and ascorbic acid). It has been shown that carbon tetrachloride causes pronounced morphologic changes in the liver and preventive use of the antihypoxants studied decreases intensity and prevalence of dystrophic processes in liver tissues. The analysis of comparative efficiency of the agents studied has been carried out.
About the Authors
E. F. Repina
Ufa Institute of Occupational Health and Human Ecology
Russian Federation
Russian Federation
Repina Elvira Faridovna
450106, Ufa
N. Yu. Khusnutdinova
Ufa Institute of Occupational Health and Human Ecology
Russian Federation
Russian Federation
Khusnutdinova Nadezhda Yurevna
450106, Ufa
G. V. Timasheva
Ufa Institute of Occupational Health and Human Ecology
Russian Federation
Russian Federation
Timasheva Gulnara Vilevna
450106, Ufa
S. S. Baigil’din
Ufa Institute of Occupational Health and Human Ecology
Russian Federation
Russian Federation
Baigildin Samat Sagadatovich
450106, Ufa
D. O. Karimov
Ufa Institute of Occupational Health and Human Ecology
Russian Federation
Russian Federation
Karimov Denis Olegovich
450106, Ufa
L. A. Musina
All-Russian Centre of Eye and Plastic Surgery
Russian Federation
Russian Federation
Musina Lyalya Akhiyarovna
450075, Ufa
V. A. Myshkin
Ufa Institute of Occupational Health and Human Ecology
Russian Federation
Russian Federation
Myshkin Vladimir Alexandrovich
450106, Ufa
A. V. Bakirov
Ufa Institute of Occupational Health and Human Ecology
Russian Federation
Russian Federation
Bakirov Ahat Barievich
450106, Ufa
A. R. Gimadieva
Ufa Institute of Chemistry of the Russian Academy of Science
Russian Federation
Russian Federation
Gimadieva Alfiya Raisovna
450054, Ufa
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Review
For citations:
Repina E.F., Khusnutdinova N.Yu., Timasheva G.V., Baigil’din S.S., Karimov D.O., Musina L.A., Myshkin V.A., Bakirov A.V., Gimadieva A.R. MORPHOLOGIC SPECIFICITIES OF HEPATOPROTECTIVE EFFECTS OF ANTIHYPOXANTS IN EXPERIMENTAL ACUTE LIVER DAMAGE WITH CARBON TETRACHLORIDE. Toxicological Review. 2019;(1):43-48. (In Russ.) https://doi.org/10.36946/0869-7922-2019-1-43-48
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