STUDY OF THE TOXIC PROPERTIES OF 3-CHLOROPROPYL AND 6-CHLOROHEXYL ACRYLATES WITH JUSTIFICATION OF APPROXIMATELY SAFE LEVEL OF EXPOSURE IN THE AIR OF THE WORKING AREA
https://doi.org/10.36946/0869-7922-2019-5-26-32
Abstract
The article presents the results of the study on toxicity of 3-chloropropyl and 6-chlorohexyl acrylates in acute (at the level of lethal and sublethal doses and concentrations) and subchronic experiments (dose-monotone intake at the level of 0.1 DL50 per os for 45 days), which allowed to justify the value of approximately safe levels of exposure for chemicals in the air of the working area. Scientifically substantiated values of approximately safe exposure levels for 3-chloropropyl acrylate at 5 mg/m3 and for 6-chlorohexyl acrylate at 2 mg/m3 have been established.
About the Authors
S. I. Sychik
Scientific Practical Centre of Hygiene, Ministry of Health of the Republic of Belarus
Belarus
Belarus
Sychik Sergei Ivanovich
220012, MinskV. M. Vasilkevich
Scientific Practical Centre of Hygiene, Ministry of Health of the Republic of Belarus
Belarus
Belarus
Vasilkevich Vadim Michailovich
220012, MinskR. V. Bogdanov
Scientific Practical Centre of Hygiene, Ministry of Health of the Republic of Belarus
Belarus
Belarus
Bogdanov Ruslan Valerievich
220012, Minsk
L. M. Bondarenko
Scientific Practical Centre of Hygiene, Ministry of Health of the Republic of Belarus
Belarus
Belarus
Bondarenko Ljudmila Mihailovna
220012, Minsk
A. V. Bujnickaja
Scientific Practical Centre of Hygiene, Ministry of Health of the Republic of Belarus
Belarus
Belarus
Bujnickaja Anna Vasil’evna
220012, Minsk
References
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Review
For citations:
Sychik S.I., Vasilkevich V.M., Bogdanov R.V., Bondarenko L.M., Bujnickaja A.V. STUDY OF THE TOXIC PROPERTIES OF 3-CHLOROPROPYL AND 6-CHLOROHEXYL ACRYLATES WITH JUSTIFICATION OF APPROXIMATELY SAFE LEVEL OF EXPOSURE IN THE AIR OF THE WORKING AREA. Toxicological Review. 2019;(5):26-32. (In Russ.) https://doi.org/10.36946/0869-7922-2019-5-26-32
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