DIAGNOSIS TRAITS OF CHRONIC MANGANISM DEFINED BY NEUROBEHAVIORAL TESTS
Abstract
Based on investigations carried out, the information capacity of some neuro behavioral tests was established in the course of clinical diagnosis of manganese intoxication in arc-welders exposed to welding aerosol. The average length of service of arc-welders was 19.5 years. The most clear differences were noted in performing stability static test, fingerprint test, fine motor skills assessment. A recommended application algorithm of neuro behavioral tests can be used in early diagnosis of initial manifestations of manganese intoxication as a result of occupational exposure to welding aerosol.
About the Authors
Evgeny Vladimirovich Zibarev
Northwest Scientific Center of Hygiene and Public Health
Russian Federation
Russian Federation
Sofia Maksimovna Nikonova
Northwest Scientific Center of Hygiene and Public Health
Russian Federation
Russian Federation
Valery Petrovich Chashhin
Northwest Scientific Center of Hygiene and Public Health
Russian Federation
Russian Federation
Viktor Vasilievich Shilov
Northwest Scientific Center of Hygiene and Public Health
Russian Federation
Russian Federation
Dag G. Ellingsen
Национальный институт профессионального здоровья
Yngvar Tomassen
Vladimir Nikolaevich Fedorov
Northwest Scientific Center of Hygiene and Public Health
Russian Federation
Russian Federation
V. I. Masalova
Northwest Scientific Center of Hygiene and Public Health
Russian Federation
Russian Federation
References
1. Gorban’ L. N., Kucheruk T. K., Lubjanova I. P. Biologicheskj vozrast jelektrosvarshhikov. Gerontologja i geriatrja. Vsesojuznoe nauchnoe obshhestvo gerontologov i geriatrov, Institut gerontologii AMN SSSR. M., 1988. #6. - S.69-72. (in Russian)
2. Zibarev E.V., Chashhin M.V., Kuz’min A.V., Zaharova N.V, Pochkarjov I.I. Primenenie nejropsihologicheskih testov dlja rannej diagnostiki hronicheskoj margancevoj intoksikacii. V kn.: Materialy X s”ezda gigienistov i sanitarnyh vrachej, M.: 2008. kn. 1. - S. 132-134 (in Russian)
3. Zibarev E.V. Chashhin M.V., Ellingsen D.G., Z.S. Kusraeva, i dr. Osobennosti funkcional’nogo sostojanja nervnoj sistemy jelektrosvarshhikov, podvergshihsja vozdejstvju soedinenj marganca. Medicina truda i promyshlennaja jekologja, 2009. - #4. -S. 9-14. (in Russian)
4. Zibarev E.V., Chashhin M.V., Nikonova S.M., Kusraeva Z.S., Kuz’min A.V., Tomassen D.G. i dr. Ocenka biomarkerov jekspozicii k svarochnomu ajerozolju. Medicina truda i promyshlennaja jekologja. 2010. 4: 14-17. (in Russian)
5. Izmerov N.F., Kasparov A.A., Korbakova A.I. i dr. Rukovodstvo po gigiene truda v 2-uh t.- M.: Medicina, 1987.- T.2.-448 s. (in Russian)
6. Dag G Ellingsen, Maxim Chashchin, Rita Bast-Pettersen, Evgenj Zibarev, Yngvar Thomassen, Valery Chashchin. A followup study of neurobehavioral functions in welders exposed to manganese. NeuroToxicology. 47 (2015) 8-16.
7. Ellingsen D.G., Konstantinov R., Bast-Pettersen R., Merkurjeva L., Chashchin M., Tomassen Y., et al. A neurobehavioral study of current and former welders exposed to manganese. NeuroToxicology. 2008. 29: 48-59.
8. Ellingsen DG, Kusraeva Z, Bast-Pettersen R, Zibarev E, Chashchin M, Thomassen Y, Chashchin V. The interaction between manganese exposure andalcohol on neurobehavioral outcomes in welders». Neurotoxicol Teratol. 2014 Jan-Feb;41:8-15.
9. Olanow C.W., Good P.F., Shinotoh H., Hewitt K.A., Vingerhoets F., SnowB.J., Beal M.F., Calne D.B., Perl D.P. Manganese intoxication in the rhesus monkey:A clinical, imaging, pathologic, and biochemical study. Neurology 1996; 46: 492-498.
10. Matthews C.G., Klove H., Madison, W.I. Instruction manual for the adult neuropsychological test battery.: University of Wisconsin Medical School, 1964
Review
For citations:
Zibarev E.V., Nikonova S.M., Chashhin V.P., Shilov V.V., Ellingsen D.G., Tomassen Y., Fedorov V.N., Masalova V.I. DIAGNOSIS TRAITS OF CHRONIC MANGANISM DEFINED BY NEUROBEHAVIORAL TESTS. Toxicological Review. 2015;(4):12-17. (In Russ.)
Views:
195
Email this article 