NEPHROPROTECTIVE ACTION OF COMBINATION OF TAURINE WITH ZINC DIASPARTATE IN RATS WITH GENTAMICIN NEPHROPATHY
Abstract
In rats with gentamicin nephropathy (gentamicin injected intra-abdominally, 60 mg/kg daily over 10 days), a combination of taurine with zinc diaspartate administrated in the stomach in the ratio of 1.0 g + 0.14g -250 mg/kg and particularly of 1.0+0.06 g - 500 mg/ kg ) has a nephroprotective effect that is proved by weakened lesions of cortical nephrons proximal convoluted tubules.
About the Authors
Olga Nikolaevna Basalai
Education establishment «Grodno State Medical University» of Ministry of health of Republic of Belarus: M.V. Korablev
Russian Federation
Russian Federation
Elena Cheslavovna Mikhalchuk
Education establishment «Grodno State Medical University» of Ministry of health of Republic of Belarus: M.V. Korablev
Russian Federation
Russian Federation
Sergey Mikhaylovich Zimatkin
Education establishment «Grodno State Medical University» of Ministry of health of Republic of Belarus: M.V. Korablev
Russian Federation
Russian Federation
Mikhail Ivanovich Bushma
Education establishment «Grodno State Medical University» of Ministry of health of Republic of Belarus: M.V. Korablev
Russian Federation
Russian Federation
Olga Aleksandrovna Borisenok
Education establishment «Grodno State Medical University» of Ministry of health of Republic of Belarus: M.V. Korablev
Russian Federation
Russian Federation
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Review
For citations:
Basalai O.N., Mikhalchuk E.Ch., Zimatkin S.M., Bushma M.I., Borisenok O.A. NEPHROPROTECTIVE ACTION OF COMBINATION OF TAURINE WITH ZINC DIASPARTATE IN RATS WITH GENTAMICIN NEPHROPATHY. Toxicological Review. 2015;(5):21-24. (In Russ.)
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