Multidisciplinary approach in clinical toxicology in a multidisciplinary emergency hospital (literature review)

The article considers the implementation of the concept of an interdisciplinary (multidisciplinary) approach at all stages of providing emergency medical care to patients with acute poisoning using multimodal technologies in the diagnosis, treatment and rehabilitation of toxic lesions. It is noted that clinical toxicology is closely related to a number of fundamental medical sciences, and the share of advisory assistance from related specialists in the structure of medical services for this pathology is high. Using the example of a multidisciplinary emergency hospital, the key role of interdisciplinary interaction is demonstrated.

The work is based on the analysis of data from international (Scopus, Web of Science, PubMed) and Russian (RSCI, eLibrary.RU, CyberLeninka) scientific databases.

The systematic introduction of interdisciplinary interaction into clinical practice is a prerequisite for improving the effectiveness and quality of medical care in acute poisoning.

Authors’ contribution:
Antonova A.M. – concept and design of research, collection and processing of material, writing, editing;
Lodyagin A.N., Barsukova I.M., Batotsyrenov B.V. – concept and design of research, writing, editing;
Narzikulov R.A., Sinenchenko A.G. – writing, editing;
Kuznetsov S.V., Shikalova I.A. – collecting and processing of material, writing text, editing.
All co-authors are responsible for approving the final version of the article and ensuring the integrity of all its parts.

Conflict of interest. The authors declare that there are no obvious and potential conflicts of interest in connection with the publication of this article.

Funding. The study had no financial support

Received: February 6, 2026 / Revised: March 30, 2026 / Accepted: June 1, 2026 / Published: June 30, 2026

1. Fedotova I.N., Vasina T.A., Belopolsky A.A., Kuznetsov V.I., Mansur T.I. Neurotoxicity of acute poisoning. Zemskii vrach. 2013; (1): 32–4. https://elibrary.ru/pxvhhl (in Russian)

2. Gladkikh V.D. Medical rehabilitation in acute poisoning. Sovremennye voprosy biomeditsiny. 2018; 2(2): 54–62. https://elibrary.ru/xqrwuh (in Russian)

3. Trofimova T.N., Sofronov G.A., Belyakov N.A., Medvedev S.V. Radiologic diagnosis of cerebral toxic lesions. Luchevaya diagnostika i terapiya. 2011; (1): 37–46. https://elibrary.ru/nuunzx (in Russian)

4. Spencer P. S., Schaumburg H.Н., eds. Experimental and Clinical Neurotoxicology. Part One: Fundamentals of Experimental and Clinical Neurotoxicology. Oxford: Oxford University Press; 2015.

5. Golovko A.I., Sofronov G.A., Sofronov A.G. Toxicological paradoxes in modern narcology. Toksikologicheskii vestnik. 2015; (1): 2–9. https://elibrary.ru/ywwcvy (in Russian)

6. Belyakov N.A., Trofimova T.N., Rassokhin V.V., Shelomov A.S., Magonov Ye.P., Bogdan A.A., et al. The interdisciplinary, personalized approach and brain investigation technology in HIV infection. Luchevaya diagnostika i terapiya. 2020; (2): 7–28. https://doi.org/10.22328/2079-5343-2020-11-2-7-28 https://elibrary.ru/vqxiso (in Russian)

7. Ivanykina T.V. Medical and Biological Safety Fundamentals. Part 2. Fundamentals of Toxicology [Mediko-biologicheskie osnovy bezopasnosti. Chast’ 2. Osnovy toksikologii]. Blagoveshchensk; 2023. (in Russian)

8. Zakharova F.A., Fedorova N.F. Multidisciplinary approach in the diagnosis of COVID-19. In: Integration of Sciences: Interdisciplinarity in Medicine. WCMIF-2022. Collection of Abstracts of the All-Russian Scientific and Practical Conference with International Participation [Integratsiya nauk: mezhdistsiplinarnost’ v meditsine. VKMIF-2022. Sbornik tezisov Vserossiiskoi nauchno-prakticheskoi konferentsii s mezhdunarodnym uchastiem]. Yakutsk; 2022: 117–9. (in Russian)

9. Zhong X., Zeng X., Zhao L., Chen T., Min X., He R. Clinicians’ knowledge and understanding regarding multidisciplinary treatment implementation: a study in municipal public class III grade A hospitals in Southwest China. BMC Med. Educ. 2023; 23(1): 916. https://doi.org/10.1186/s12909-023-04891-0 https://elibrary.ru/qfnbjt

10. Taberna M., Gil Moncayo F., Jané-Salas E., Antonio M., Arribas L., Vilajosana E., et al. The multidisciplinary team (MDT) approach and quality of care. Front. Oncol. 2020; 10: 85. https://doi.org/10.3389/fonc.2020.00085 https://elibrary.ru/wqknfj

11. Sultanov R.R. Interdisciplinary interaction of doctors as one of the ways to increase the effectiveness of the treatment process. Gumanitarnye i sotsial’nye nauki. 2013; (2): 231–43. https://elibrary.ru/rsjgbd (in Russian)

12. Zagorulko O.I., Medvedeva L.A., Kukushkin M.L. Interdisciplinary approach in research and treatment of pain. Rossiiskii zhurnal boli. 2021; 19(2): 42–6. https://doi.org/10.17116/pain20211902142 https://elibrary.ru/ldglde (in Russian)

13. Nesterov A.V. Once again about scientific disciplines, cross-disciplinary, multidisciplinary, polidisciplinary and trans-disciplinary approach; 2018. Available at: https://nesterov.su/еще-раз-о-научных-дисциплинах-междисц/ (in Russian)

14. Danilov A.B., Danilov A.B., Kurushina O.V., Barulin A.E. Interdisciplinary medicine. Terapiya. 2017; (7): 6–11. https://elibrary.ru/zvmsyj (in Russian)

15. Igumnov S.A., Stanko E.P. Dynamics of psychopathological symptomatology in patients with opioid dependence in the process of treatment. Vestnik psikhiatrii i psikhologii Chuvashii. 2015; 11(3): 83–99. https://elibrary.ru/vnxgsx (in Russian)

16. Agibalova T.V., Tuchin P.V., Tuchina O.D. Clinical guidelines for medical rehabilitation of patients with addictive disorders: psychotherapy in medical rehabilitation programs. Voprosy narkologii. 2015; (3): 87–106. https://elibrary.ru/uapxth (in Russian)

17. Masyakin A.V., Agibalova T.V., Borovkov E.I., Shipitsyn V.V., Laktaeva E.A., Semenyaka I.V., et al. Medical Rehabilitation Program for Adults with Drug-Related Disorders (ICD-10 F10-F19) [Programma meditsinskoi reabilitatsii dlya vzroslogo naseleniya s narkologicheskimi rasstroistvami (MKB-10 F10-F19)]. Moscow; 2024. Available at: https://niioz.ru/upload/iblock/4ba/4ba8d678740d51a824fd3bb47bb50661.pdf (in Russian)

18. Pecherina O.I. Psychological Intervention in the Medical and Social Rehabilitation of Drug-Related Patients: Organization and Content [Psikhologicheskaya interventsiya pri mediko-sotsial’noi reabilitatsii narkologicheskikh bol’nykh: organizatsiya i soderzhanie]. Chelyabinsk; 2017. (in Russian)

19. Ilyuk R.D., Berno-Bellekur I.V., Torban M.N., Krupitskii E.M. Dynamic Assessment of Clinical and Social Characteristics of Opiate Drug Users Undergoing Rehabilitation Treatment [Dinamicheskaya otsenka klinicheskikh i sotsial’nykh kharakteristik nakhodyashchikhsya na reabilitatsionnom lechenii potrebitelei opiatnykh narkotikov]. St. Petersburg; 2012. (in Russian)

20. Skalin Yu.E., Krylova N.V. Psychodiagnostic Patient Support at the Adaptive, Integration and Stabilization Stages of the Treatment and Rehabilitation Process [Psikhodiagnosticheskoe soprovozhdenie patsienta na adaptatsionnom, integratsionnom i stabilizatsionnom etapakh lechebno-reabilitatsionnogo protsessa]. Kaliningrad; 2013. https://elibrary.ru/yzuzdv (in Russian)